Researchers of Belgorod State University discover genes provoking peptic ulcer disease

In July 2021 a group of scientists from Belgorod State University began to explore the genetic factors responsible for peptic ulcer development. The disease may be triggered by Helicobacteriosis infection, unhealthy diet, unhealthy habits and the use of strong medicine. Belgorod scientists found out that not only lifestyle, but also genes are often involved in provoking peptic ulcer disease.

RIA Novosti have recently published the results of a joint study by Belgorod State University and Al-Faisal University (Saudi Arabia) researches who presented their scientific paper describing the relation between proteolytic enzyme genes and duodenal ulcers. It is notable that this relation is seen in the population of Central Russia while the risks may be different in other countries.

Initially the researchers were interested in the fact that some patients suffer from peptic ulcer even with a proper diet and healthy lifestyle, while others do not develop the disease even being exposed to negative factors. Mikhail Churnosov, the Head of BelSU Department of Medical and Biological Disciplines noted that such 'behaviour' of the disease may be due to the genetic predisposition.

Modern methods of molecular genetic analysis and genetic-statistical analysis of experimental data were used in the work. The results of the study can already be used in gastroenterology and identify risk groups in healthy populations. This will help to control the disease development and initiate targeted treatment at the early stage.